Sulfonamiden betekenis

Sulfonamiden: Antibiotica voor infecties en darmziekten Sulfonamiden, oftewel sulfamedicijnen, vormen een groep synthetische geneesmiddelen die de chemische sulfonamidengroep bevatten. Deze antimicrobiële middelen zijn bacteriostatisch, wat betekent dat ze de groei en voortplanting van bacteriën remmen zonder deze direct te doden. Lees meer over sulfonamiden, een klasse geneesmiddelen die worden gebruikt om verschillende bacteriële infecties te behandelen. Ontdek hoe sulfonamiden werken, hun werkingsmechanisme en hun mogelijke bijwerkingen. Ontdek wanneer sulfonamiden worden voorgeschreven en welke voorzorgsmaatregelen moeten worden genomen bij het gebruik ervan. Sulfonamiden betekenis Sulfonamides (sulphonamides) are a group of man-made (synthetic) medicines that contain the sulfonamide chemical group. They may also be called sulfa drugs and are used for a wide range of conditions from diabetes to pain relief.

Antibiotica

Learn about antibiotics, a class of drugs that treat bacterial infections. Find out how to use them correctly, when to avoid them, and what are the common names and classes of antibiotics. Antibiotics are substances that kill or inhibit bacteria and are used to treat or prevent infections. Learn about the origin, classification, medical uses and challenges of antibiotics, such as antimicrobial resistance and access. Antibiotica Antibiotics work by killing bacteria and preventing them from multiplying. Common antibiotics include penicillin and amoxicillin. Doctors may also use azithromycin and doxycycline for certain.

Sulfamedicijnen

Sulfa drugs are synthetic (man-made) medications made from sulfanilamide that contain antibacterial properties. Sulfa drugs were the first class of antibiotics ever discovered. However, many other medications may contain sulfa too, such as medications for diabetes, thyroiditis, and arthritis. Sulfonamides (sulphonamides) are a group of man-made (synthetic) medicines that contain the sulfonamide chemical group. They may also be called sulfa drugs. Many people use the term sulfonamide imprecisely to refer only to antibiotics that have a sulfonamide functional group in their chemical structure.

Sulfamedicijnen Sulfonamiden, ook bekend als sulfamedicijnen, zijn een klasse medicijnen die al tientallen jaren in de geneeskunde worden gebruikt. Ze behoren tot de groep antibiotica en worden voornamelijk gebruikt om bacteriële infecties te behandelen.

Sulfonamide resistentie

Sulfonamides were the first drugs acting selectively on bacteria which could be used systemically. Today they are infrequently used, in part due to widespread resistance. The target of sulfonamides, and the basis for their selectivity, is the enzyme dihydropteroate synthase (DHPS) in the folic acid . Bacterial resistance to sulfonamide antibiotics (sulfas) is mediated by acquisition of sul genes, which encode sulfa-insensitive versions of the target enzyme, dihydropteroate synthase.

Sulfonamide resistentie In many pathogenic bacteria sulfonamide resistance is mediated by the horizontal transfer of foreign folP or parts of it. Clinical resistance in gram-negative enteric bacteria is plasmid-borne and is effected by genes encoding alternative drug-resistance variants of the DHPS enzymes.

Werking sulfonamiden

In vivo sulfonamides exhibit a range of pharmacological activities, such as anti-carbonic anhydrase and anti-t dihydropteroate synthetase allowing them to play a role in treating a diverse range of disease states such as diuresis, hypoglycemia, thyroiditis, inflammation, and glaucoma. Sulfonamiden hebben een breed werkingsspectrum dat zowel Gram-positieve als Gram-negatieve bacteriën omvat. De meeste bacteriesoorten worden voor sulfonamiden relatief snel resistent.

Werking sulfonamiden